(+)-Xestospongin A
Item № 10006794
CAS № 88840-02-2
Purity ≥90%
product image
        (CAS 88840-02-2)
50 µg $165.00 $0.00
100 µg $314.00 $0.00
250 µg $743.00 $0.00

Pricing updated 2016-02-08. Prices are subject to change without notice.

Bulk Inquiry Form


Enter number, size, and select unit. Example: 2 x 500 mg

Please indicate any analytical testing requirements, special handling, packaging, or delivery requirements.

  • Araguspongin D
  • XeA

Xestospongins are marine natural products first isolated from pacific basin sponges, and noted to have vasodilatory properties.1 Inositol phosphates (IPs) are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores.2 XestosponginA antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate at the receptor level in cerebral microsomes, with an IC50 of 2.5 µM.3 It is thus about ten times less potent than XestosponginC as an antagonist of the IP3 receptor.

Download Product Insert Download Safety Data Sheet (SDS)

Related Products
View Related Product Categories
Technical Information
Formal Name [1R-(1R*,4aR*,11R*,12aS*,13R*,16aR*,23R*,24aS*)]-eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacyclo-eicosino[2,3-b:12,13-b’]dipyridine
CAS Number 88840-02-2
  • Araguspongin D
  • XeA
Molecular Formula C28H50N2O2
Formula Weight 446.7
Purity ≥90%
Formulation A solution in acetone
InChI Code 1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24-,25-,26-,27-,28-/m1/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Separate multiple batch numbers with commas

QC Sheets
Certificates of Analysis
References & Background Reading
Product Description References

1. Nakagawa, M., and Endo, M. Structures of xestospongin A, B, C and D, novel vasodilative compounds from marine sponge, Xestospongia exigua. Tetrahedron Lett 25(30) 3227-3230 (1984).

2. Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

3. Gafni, J., Munsch, J.A., Lam, T.H., et al. Xestospongins: Potent membrane permeable blockers of the inositol 1,4,5-triphosphate receptor. Neuron 19 723-733 (1997).

Technical Support
Contact Us
  • To streamline the process attach the appropriate questionnaire to your inquiry.

  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Contract Research Services

We offer you the deep and diverse knowledge of more than 100 in-house scientists and the expertise that comes from more than three decades of designing and developing the tools to advance biomedical research.

Cayman is know as a partner to scientists worldwide, responding to your needs with services in:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA


Please wait...