5(S)-HETE Lipid Maps MS Standard
Item № 10007243
CAS № 70608-72-9
Purity >98%
product image
        (CAS 70608-72-9)
25 µg $98.00 $0.00
50 µg $176.00 $0.00
100 µg $329.00 $0.00
250 µg $737.00 $0.00

Pricing updated 2016-02-11. Prices are subject to change without notice.

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5(S)-HETE is produced by the action of 5-LO on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes.1 When further metabolized to 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4.2,3

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Technical Information
Formal Name 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
CAS Number 70608-72-9
Molecular Formula C20H32O3
Formula Weight 320.5
Purity >98%
Formulation A solution in ethanol

WARNING - This product is for laboratory research only. Not for administration to humans. Not for human or veterinary diagnostic or therapeutic use.

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Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
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References & Background Reading
Product Description References

1. Dodge, W., and Thomas, M. The effect of 5-hydroxyeicosatetraenoic acid on the proliferation of granulocyte progenitors and embryonic fibroblasts of the chick. Biochem Biophys Res Commun 131 731-735 (1985).

2. Schwenk, U., and Schr�der, J. 5-oxo-Eicosanoids are potent eosinophil chemotactic factors. J Biol Chem 270 15029-15036 (1994).

3. Powell, W.S., Gravelle, F., and Gravel, S. Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxyeicosanoids by a specific dehydrogenase in human polymorphonuclear leukocytes. J Biol Chem 267 19233-19241 (1992).

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