12-OxoETE Lipid Maps MS Standard
Item № 10007249
CAS № 108437-64-5
Purity ≥90%
25 µg $116.00 $0.00
50 µg $220.00 $0.00
100 µg $418.00 $0.00
250 µg $928.00 $0.00

Pricing updated 2016-04-30. Prices are subject to change without notice.

Bulk Inquiry Form


Enter number, size, and select unit. Example: 2 x 500 mg

Please indicate any analytical testing requirements, special handling, packaging, or delivery requirements.

  • 12-KETE

12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid.1,2 Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE.1,3 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via an Leukotriene B4 receptor or a common activation sequence.4

Download Product Insert Download Safety Data Sheet (SDS)

Related Products
View Related Product Categories
Technical Information
Formal Name 12-oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid
CAS Number 108437-64-5
  • 12-KETE
Molecular Formula C20H30O3
Formula Weight 318.5
Purity ≥90%
Formulation A solution in ethanol

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
Stability As supplied, 6 months from the QC date provided on the Certificate of Analysis, when stored properly
Product Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Separate multiple batch numbers with commas

QC Sheets
Certificates of Analysis
References & Background Reading
Product Description References

1. Falgueyret, J., Leblanc, Y., and Riendeau, D. Stereoselective carbonyl reductases from rat skin and leukocyte microsomes converting 12-ketoeicosatetraenoic acid to 12(S)-HETE. FEBS Lett 262 197-200 (1990).

2. Fruteau De Laclos, B., Maclouf, J., Poubelle, P., et al. Conversion of arachidonic acid into 12-oxo derivatives in human platelets. A pathway possibly involving the heme-catalysed transformation of 12-hydroperoxy-eicosatetraenoic acid. Prostaglandins 33 315-337 (1987).

3. Falgueyret, J., Leblanc, Y., Rokach, J., et al. NAD(P)H-dependent reduction of 12-ketoeicosatetraenoic acid to 12(R)-hydroxyeicosatetraenoic acid by rat liver microsomes. Biochem Biophys Res Commun 156 1083-1089 (1988).

4. Naccache, P.H., Leblanc, Y., Rokach, J., et al. Calcium mobilization and right-angle light scatter responses to 12-oxo-derivatives of arachidonic acid in neutrophils: Evidence for the involvement of the leukotriene B4 receptor. Biochim Biophys Acta 1133 102-106 (1991).

Technical Support
Contact Us
  • To streamline the process attach the appropriate questionnaire to your inquiry.

  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Contract Research Services

We offer you the deep and diverse knowledge of more than 100 in-house scientists and the expertise that comes from more than three decades of designing and developing the tools to advance biomedical research.

Cayman is know as a partner to scientists worldwide, responding to your needs with services in:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA