12(S)-HHTrE Lipid Maps MS Standard
Item № 10007250
CAS № 54397-84-1
Purity ≥97%
25 µg $109.00 $0.00
50 µg $207.00 $0.00
100 µg $392.00 $0.00
250 µg $872.00 $0.00

Pricing updated 2016-05-02. Prices are subject to change without notice.

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  • 12-HHT

12(S)-HHTrE is an unusual product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of the human platelet.1 It is biosynthesized by thromboxane (TX) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. The biological role of 12(S)-HHTrE is uncertain. It is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.2

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Technical Information
Formal Name 12S-hydroxy-5Z,8E,10E-heptadecatrienoic acid
CAS Number 54397-84-1
  • 12-HHT
Molecular Formula C17H28O3
Formula Weight 280.4
Purity ≥97%
Formulation A solution in ethanol

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Diczfalusy, U., Falardeau, P., and Hammarström, S. Conversion of prostaglandin endoperoxides to C17-hydroxy acids catalyzed by human platelet thromboxane synthase. FEBS Lett 84 271-274 (1977).

2. Liu, Y., Yoden, K., Shen, R., et al. 12-L-Hydroxy-5,8,10-heptadecatrienoic acid (HHT) is an excellent substrate for NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. Biochem Biophys Res Commun 129 268-274 (1985).

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