Item № 10008588
Purity ≥97%
500 µg $107.00 $0.00
1 mg $203.00 $0.00
5 mg $856.00 $0.00
10 mg $1,498.00 $0.00

Pricing updated 2016-05-26. Prices are subject to change without notice.

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  • 5-cis-15(R)-Ciloprost

5-cis-15(R)-Iloprost is the C-5 cis-isomer and 15(R)-epimer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.1 There are no published studies of the pharmacological properties of 5-cis-15(R)-iloprost.

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Technical Information
Formal Name 6,9α-methylene-11α,15R-dihydroxy-16-methyl-prosta-5Z,13E-dien-18-yn-1-oic acid
  • 5-cis-15(R)-Ciloprost
Molecular Formula C22H32O4
Formula Weight 360.5
Purity ≥97%
Formulation A solution in methyl acetate
SMILES O[C@@H]1C[C@H]2[C@H](C/C(C2)=C\CCCC(O)=O)[C@H]1/C=C/[C@H](O)C(C)CC#CC
InChI Code 1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8-/t15?,17-,18+,19-,20-,21+/m0/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Schrör, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) - equipotent to PGI2 in vitro. Naunyn Schmiedebergs Arch Pharmacol 316 252-255 (1981).

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