Pinolenic Acid
Item № 10008654
CAS № 16833-54-8
Purity ≥98%
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        (CAS 16833-54-8)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
10 mg $19.00 $0.00
25 mg $45.00 $0.00
50 mg $86.00 $0.00
100 mg $152.00 $0.00

Pricing updated 2016-02-11. Prices are subject to change without notice.

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Description

Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils. Both oils have been found to have lipid-lowering properties. A diet containing maritime pine seed oil (MPSO) lowered HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux in vitro.1 Korean pine seed oil supplements may help in obesity by reduction of appetite. People taking this oil had an increase in the satiety hormones CCK and GLP-1 and a reduced desire to eat.2 The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not converted to arachidonic acid metabolically and can reduce arachidonic acid levels in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%.3

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Technical Information
Formal Name 5Z,9Z,12Z-octadecatrienoic acid
CAS Number 16833-54-8
Molecular Formula C18H30O2
Formula Weight 278.4
Purity ≥98%
Formulation A solution in ethanol
SMILES CCCCC/C=C\C/C=C\CC/C=C\CCCC(=O)O
InChI Code 1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10,13-14H,2-5,8,11-12,15-17H2,1H3,(H,19,20)/b7-6-,10-9-,14-13-
InChI Key HXQHFNIKBKZGRP-URPRIDOGSA-N

WARNING - This product is for laboratory research only. Not for administration to humans. Not for human or veterinary diagnostic or therapeutic use.

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Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 1 year
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References & Background Reading
Product Description References

1. Asset, G., Leroy, A., Bauge, E., et al. Effects of dietary maritime pine (Pinus pinaster)-seed oil on high-density lipoprotein levels and in vitro cholesterol efflux in mice expressing human apolipoprotein A-I. Br J Nutr 84 353-360 (2000).

2. Causey, J.L. Korean pine nut fatty acids induce satiety-producing hormone release in overweight human volunteers. The 231st ACS National Meeting (2006 28 March).

3. Tamotsu, T., Tatsunori, T., Morishige, J., et al. Non-methylene-interrupted polyunsaturated fatty acids: Effective substitute for arachidonate of phosphatidylinositol. Biochem Biophys Res Commun 264 683-688 (1999).

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