CAY10506
Item № 10009079
CAS № 292615-75-9
Purity ≥98%
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $35.00 $0.00
5 mg $158.00 $0.00
10 mg $280.00 $0.00
50 mg $1,225.00 $0.00

Pricing updated 2016-05-02. Prices are subject to change without notice.

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Description

Anti-diabetic drugs of the thiazolidinedione (TZD) structural class as well as α-lipoic acid activate peroxisome proliferator-activated receptor γ (PPARγ), a nuclear transcription factor that controls glucose metabolism and lipid homeostasis. CAY10506 is a hybrid lipoic acid-TZD derivative that transactivates human PPARγ with an EC50 value of 10 µM.1

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Technical Information
Formal Name N-[2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]ethyl]-1,2-dithiolane-3-pentanamide
CAS Number 292615-75-9
Molecular Formula C20H26N2O4S3
Formula Weight 454.6
Purity ≥98%
Formulation A solution in methyl acetate
SMILES O=C(CCCCC1SSCC1)NCCOc1ccc(cc1)CC1SC(=O)NC1=O
InChI Code 1S/C20H26N2O4S3/c23-18(4-2-1-3-16-9-12-27-29-16)21-10-11-26-15-7-5-14(6-8-15)13-17-19(24)22-20(25)28-17/h5-8,16-17H,1-4,9-13H2,(H,21,23)(H,22,24,25)
InChI Key VDWFJOXRKJFJMP-UHFFFAOYSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
Product Downloads & Resources
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Additional Information

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References & Background Reading
Product Description References

1. Chittiboyina, A.G., Venkatraman, M.S., Mizuno, C.S., et al. Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPAR.gamma. agonists. J Med Chem 49 4072-4084 (2006).

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