15-deoxy-Δ12,14-Prostaglandin A1
Item № 10065
CAS № 573951-20-9
Purity ≥95%
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
500 µg $78.00 $0.00
1 mg $117.00 $0.00
5 mg $546.00 $0.00

Pricing updated 2016-05-26. Prices are subject to change without notice.

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Description
Synonyms
  • 15-deoxy-Δ12,14-PGA1

15-deoxy-Δ12,14-Prostaglandin A1 (15-deoxy-Δ12,14-PGA1) is a synthetic PGA1 analog. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.1 Antimitotic and antitumor activity have been reported for a similar analog, but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA1 at this time.2

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Technical Information
Formal Name 9-oxo-prosta-10,12Z,14E-trien-1-oic acid
CAS Number 573951-20-9
Synonyms
  • 15-deoxy-Δ12,14-PGA1
Molecular Formula C20H30O3
Formula Weight 318.5
Purity ≥95%
Formulation A solution in methyl acetate
λmax 324 nm
SMILES CCCCC/C=C/C=C1\C=CC(=O)C\1CCCCCCC(=O)O
InChI Code 1S/C20H30O3/c1-2-3-4-5-6-9-12-17-15-16-19(21)18(17)13-10-7-8-11-14-20(22)23/h6,9,12,15-16,18H,2-5,7-8,10-11,13-14H2,1H3,(H,22,23)/b9-6+,17-12-/t18-/m1/s1
InChI Key LDOCIRJMPUHXRM-YUJGFSRTSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Kliewer, S.A., Lenhard, J.M., Willson, T.M., et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor .gamma. and promotes adipocyte differentiation. Cell 83 813-819 (1995).

2. Kato, T., Fukushima, M., Kurozumi, S., et al. Antitumor activity of .DELTA.7-prostaglandin A1 and .DELTA.12-prostaglandin J2 in vitro and in vivo. Cancer Res 46 3538-3542 (1986).

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