AL 8810 isopropyl ester
Item № 10113
CAS № 208114-93-6
Purity ≥98%
1 mg $57.00 $0.00
5 mg $257.00 $0.00
10 mg $456.00 $0.00

Pricing updated 2016-05-25. Prices are subject to change without notice.

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AL 8810 (Item No. 16735) is an 11β-fluoro analog of prostaglandin F (Item No. 16010) which acts as a potent and selective antagonist at the FP receptor.1 AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost (Item No. 16812) and Travoprost.2,3 The pharmacology of AL 8810 isopropyl ester has not been published.

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Technical Information
Formal Name 9α,15R-dihydroxy-11β-fluoro-15-(2,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester
CAS Number 208114-93-6
Molecular Formula C27H37FO4
Formula Weight 444.6
Purity ≥98%
Formulation A crystalline solid
SMILES CC(C)OC(CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@H](O)C2CC3=CC=CC=C3C2)[C@@H](F)C[C@@H]1O)=O
InChI Code 1S/C27H37FO4/c1-18(2)32-27(31)12-6-4-3-5-11-23-22(24(28)17-26(23)30)13-14-25(29)21-15-19-9-7-8-10-20(19)16-21/h3,5,7-10,13-14,18,21-26,29-30H,4,6,11-12,15-17H2,1-2H3/b5-3-,14-13+/t22-,23-,24+,25+,26+/m1/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
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References & Background Reading
Product Description References

1. Griffen, B.W., Klimko, P., Crider, J.Y., et al. AL-8810: A novel prostaglandin F2.alpha. analog with selective antagonist effects at the prostaglandin F2.alpha. (FP) receptor. J Pharmacol Exp Ther 290(3) 1278-1284 (1999).

2. Camras, C.B., Alm, A., Watson, P., et al. Latanoprost, a prostaglandin analog, for glaucoma therapy. Efficacy and safety after 1 year of treatment in 198 patients. Ophthalmology 103 1916-1924 (1996).

3. Sorbera, L.A., and Castañer, J. Travoprost. Drugs Future 25 41-45 (2000).

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