Pricing updated 2016-05-03. Prices are subject to change without notice.
A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4.1 The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core.2 Histone H4 undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.1
|Purity||≥95% estimated by SDS-PAGE|
|Source||Recombinant protein expressed in E. coli|
|Amino Acids||Amino acids 1-
|Formulation||A lyophilized powder; recommended buffer for reconstitution is 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride and 20% glycerol.|
|UniProt Accession №||P62805|
WARNING - This product is not for human or veterinary use.
|Shipping||Dry ice in continental US; may vary elsewhere|
|Stability||As supplied, 6 months from the QC date provided on the Certificate of Analysis, when stored properly|
View the Cayman Structure Database for chemical structure definitions for many Cayman products
Separate multiple batch numbers with commas
1. Bhaumik, S.R., Smith, E., and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14(11) 1008-1016 (2007).
Tanaka, Y., Tawaramoto-
We offer you the deep and diverse knowledge of more than 100 in-house scientists and the expertise that comes from more than three decades of designing and developing the tools to advance biomedical research.
Cayman is know as a partner to scientists worldwide, responding to your needs with services in: