(±)-CP 47,497-d11 (exempt preparation)
Item № 10687
Purity ≥99% deuterated forms (d1-d11)
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
100 µg $110.00 $0.00
500 µg $440.00 $0.00
1 mg $660.00 $0.00

Pricing updated 2016-02-10. Prices are subject to change without notice.

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Description
Synonyms
  • CP 47,947-d11

(±)-CP 47,497-d11 (exempt preparation) contains eleven deuterium atoms at the 4, 4', 5, 5', 6, 6', 7, 7', 8, 8, and 8 positions. It is intended for use as an internal standard for the quantification of (±)-CP 47,497 (exempt preparation) by GC- or LC-mass spectrometry. CP 47,497 is a monophenol cannabimimetic compound that binds the central cannabinoid (CB1) receptor with a Ki value of 2.2 nM.1,2 It is equivalent in analgesic potency to Δ9-THC and exhibits other CB biological activities as well.

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Technical Information
Formal Name rel-5-(1,1-dimethylheptyl-3,3,4,4,5,5,6,6,7,7,7-d11)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol
Synonyms
  • CP 47,947-d11
Molecular Formula C21H23D11O2
Formula Weight 329.6
Purity ≥99% deuterated forms (d1-d11)
Formulation A solution in methanol
λmax 220, 276 nm
SMILES O[C@H]1C[C@@H](C2=CC=C(C(C)(C)CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C=C2O)CCC1
InChI Code 1S/C22H36O2/c1-4-5-6-7-8-14-22(2,3)18-12-13-20(21(24)16-18)17-10-9-11-19(23)15-17/h12-13,16-17,19,23-24H,4-11,14-15H2,1-3H3/t17-,19+/m0/s1/i1D3,4D2,5D2
InChI Key HNMJDLVMIUDJNH-LQVMWSKMSA-N
DEA Exempt Notification This product is a DEA exempt preparation of a scheduled compound - no special processing required. For larger quantities or alternate sizes, please contact sales.

WARNING - This product is for laboratory research only. Not for administration to humans. Not for human or veterinary diagnostic or therapeutic use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Additional Information

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Inserts
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References & Background Reading
Product Description References

1. Huffman, J.W., Thompson, A.L.S., Wiley, J.L., et al. Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg Med Chem 16 322-335 (2008).

2. Melvin, L.S., Milne, G.M., Johnson, M.R., et al. Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: Studies of bicyclic cannabinoid analogs. Mol Pharmacol 44 1008-1015 (1993).

Technical Support
FAQs

It appears that there is a heterogenous mixture of deuterated species in your deuterated standards; is this normal?

Yes, this is typical of our deuterated products. Our deuterated products contain less than 1 % d0. However, the labeled compounds are not 100% of the deuterated form listed on our product insert. For example, upon analysis of 2-arachidonoyl glycerol-d8 it is expected to see masses associated with the d7, d6, d5 etc.

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