Cardiogenol C (hydrochloride)
Item № 13187
CAS № 671225-39-1
Purity ≥97%
1 mg $25.00 $0.00
5 mg $113.00 $0.00
10 mg $138.00 $0.00
50 mg $563.00 $0.00

Pricing updated 2016-05-05. Prices are subject to change without notice.

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Most tissues have an endogenous pool of progenitor cells to draw from upon injury. The adult heart, however, contains a limited number of undifferentiated cells and techniques to replicate these cells from other pluripotent tissues have thus far been nonselective and inefficient. Cardiogenol C is a diaminopyrimidine compound that induces the differentiation of MHC- (myosin heavy chain) positive cardiomyocytes from embryonic stem cells with an EC50 value of 0.1 µM.1 About 90% of embryonic stem cells treated with 0.25 µM cardiogenol C express the cardiac muscle cell specific transcription factors GATA-4, MEF2, and Nkx2.5 and display the characteristic beating behavior of differentiated cardiomyocytes.1

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Technical Information
Formal Name 2-[[2-[(4-methoxyphenyl)amino]-4-pyrimidinyl]amino]-ethanol
CAS Number 671225-39-1
Molecular Formula C13H16N4O2 • HCl
Formula Weight 296.8
Purity ≥97%
Formulation A crystalline solid
InChI Code 1S/C13H16N4O2.ClH/c1-19-11-4-2-10(3-5-11)16-13-15-7-6-12(17-13)14-8-9-18;/h2-7,18H,8-9H2,1H3,(H2,14,15,16,17);1H

WARNING - This product is not for human or veterinary use.

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Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
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References & Background Reading
Product Description References

1. Wu, X., Ding, S., Ding, Q., et al. Small molecules that induce cardiomyogenesis in embryonic stem cells. J Am Chem Soc 126(6) 1590-1591 (2004).

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