9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (potassium salt)
Item № 14430
CAS № 122576-55-0
Purity ≥98%
1 mg $59.00 $0.00
5 mg $266.00 $0.00
10 mg $472.00 $0.00

Pricing updated 2016-04-28. Prices are subject to change without notice.

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  • Metenprost potassium
  • 9-deoxy-9-methylene-16,16-dimethyl PGE2 (potassium salt)
  • U-46785b

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (metenprost) is a potent analog of PGE2 with an extended half-life in vivo. In combination with various other PG derivatives, metenprost results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of metenprost and 7.5 mg of 17-phenyl trinor PGF is very effective in terminating early pregnancy.1 This PG mixture is ineffective on monkeys in their third trimester of pregnancy.1 Metenprost, when compared to PGE2 and PGF, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.1,2

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Technical Information
Formal Name 9-methylene-11α,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid, potassium salt
CAS Number 122576-55-0
  • Metenprost potassium
  • 9-deoxy-9-methylene-16,16-dimethyl PGE2 (potassium salt)
  • U-46785b
Molecular Formula C23H37O4 • K
Formula Weight 416.6
Purity ≥98%
Formulation A crystalline solid
SMILES C=C1[C@H](C/C=C\CCCC([O-])=O)[C@@H](/C=C/[C@@H](O)C(C)(C)CCCC)[C@H](O)C1.[K+]
InChI Code 1S/C23H38O4.K/c1-5-6-15-23(3,4)21(25)14-13-19-18(17(2)16-20(19)24)11-9-7-8-10-12-22(26)27;/h7,9,13-14,18-21,24-25H,2,5-6,8,10-12,15-16H2,1,3-4H3,(H,26,27);/q;+1/p-1/b9-7-,14-13+;/t18-,19+,20+,21+;/m0./s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 6 months from the QC date provided on the Certificate of Analysis, when stored properly
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References & Background Reading
Product Description References

1. Wilks, J.W. Pregnancy interception with a combination of prostaglandins: Studies in monkeys. Science 221 1407-1409 (1983).

2. Bundy, G.L., Kimball, F.A., Robert, A., et al. Synthesis and biological activity of 9-deoxo-9-methylene and related prostaglandins. Adv Prostaglandin Thromboxane Res 6 355-363 (1980).

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