17,20-dimethyl Prostaglandin F
Item № 15790
Purity ≥98%
1 mg $51.00 $0.00
5 mg $230.00 $0.00
10 mg $408.00 $0.00
25 mg $893.00 $0.00

Pricing updated 2016-04-28. Prices are subject to change without notice.

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  • 17,20-dimethyl PGF

17,20-dimethyl PGF is an analog of the limaprost family with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is an analog of PGE1 which is orally active in both rats and guinea pigs.1 The additional methyl groups in the lower side chain confer a 10-1,000 fold increase in potency over the parent compound.1 17,20-dimethyl PGF has lower side chain modifications identical to limaprost. There are no published reports describing the pharmacology of 17,20-dimethyl PGF.

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Technical Information
Formal Name 9α,11α,15S-trihydroxy-17S,20-dimethyl-prost-13E-en-1-oic acid
  • 17,20-dimethyl PGF
Molecular Formula C22H40O5
Formula Weight 384.6
Purity ≥98%
Formulation A crystalline solid
SMILES O[C@@H]1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)C[C@@H](C)CCCC)[C@H](O)C1
InChI Code 1S/C22H40O5/c1-3-4-9-16(2)14-17(23)12-13-19-18(20(24)15-21(19)25)10-7-5-6-8-11-22(26)27/h12-13,16-21,23-25H,3-11,14-15H2,1-2H3,(H,26,27)/b13-12+/t16-,17+,18+,19+,20-,21+/m0/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Tsuboi, T., Hatano, N., Nakatsuji, K., et al. Pharmacological evaluation of OP 1206, a prostaglandin E1 derivative, as an antianginal agent. Arch Int Pharmacodyn 247 89-102 (1980).

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