15(R)-15-methyl Prostaglandin F methyl ester
Item № 16734
CAS № 35700-22-2
Purity ≥98%
1 mg $42.00 $0.00
5 mg $189.00 $0.00
10 mg $336.00 $0.00

Pricing updated 2016-04-29. Prices are subject to change without notice.

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  • 15(R)-Methyl carboprost
  • 15(R)-15-methyl PGF methyl ester

15(R)-15-methyl Prostaglandin F methyl ester (15(R)-15-methyl PGF methyl ester) is a lipid soluble prodrug form of 15(R)-15-methyl PGF (Item No. 16730) with increased membrane permeability. Acid-catalyzed epimerization of 15(R)-15-methyl PGF methyl ester and hydrolysis of the ester converts it into the active 15(S)-15-methyl PGF (Item No. 16743).1,2

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Technical Information
Formal Name 9α,11α,15R-trihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid, methyl ester
CAS Number 35700-22-2
  • 15(R)-Methyl carboprost
  • 15(R)-15-methyl PGF methyl ester
Molecular Formula C22H38O5
Formula Weight 382.5
Purity ≥98%
Formulation A solution in methyl acetate
SMILES O[C@@H]1[C@H](C/C=C\CCCC(OC)=O)[C@@H](/C=C/[C@](C)(O)CCCCC)[C@H](O)C1
InChI Code 1S/C22H38O5/c1-4-5-10-14-22(2,26)15-13-18-17(19(23)16-20(18)24)11-8-6-7-9-12-21(25)27-3/h6,8,13,15,17-20,23-24,26H,4-5,7,9-12,14,16H2,1-3H3/b8-6-,15-13+/t17-,18-,19+,20-,22-/m1/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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References & Background Reading
Product Description References

1. Plaisted, S.M., DeZwaan, J., and Snider, B.G. High-performance liquid chromatographic determination of acid-catalyzed degradation products of methyl carboprost in a polymeric controlled-release device. J Chromatogr 314 369-377 (1984).

2. Hamberg, M., Zhang, L., and Bergström, S. On the pH-dependent degradation of 15(S)-15 methyl-prostaglandin F2.alpha. (carboprost). Eur J Pharm Sci 3 27-38 (1995).

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