7-hydroxycoumarinyl Arachidonate
Item № 62910
CAS № 161180-11-6
Purity ≥98%
5 mg $28.00 $0.00
10 mg $53.00 $0.00
25 mg $126.00 $0.00
50 mg $224.00 $0.00

Pricing updated 2016-05-06. Prices are subject to change without notice.

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  • Umbelliferyl Arachidonate

7-hydroxycoumarinyl Arachidonate is the arachidonic acid ester of 7-hydroxycoumarin (umbelliferone) and behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl arachidonate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).1,2

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Technical Information
Formal Name 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-oxo-2H-1-benzopyran-7-yl ester
CAS Number 161180-11-6
  • Umbelliferyl Arachidonate
Molecular Formula C29H36O4
Formula Weight 448.6
Purity ≥98%
Formulation A solution in ethanol
λmax 282, 312 nm
SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)Oc1ccc2ccc(=O)oc2c1
InChI Code 1S/C29H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(30)32-26-22-20-25-21-23-29(31)33-27(25)24-26/h6-7,9-10,12-13,15-16,20-24H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15-

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Huang, Z., Laliberté, F., Tremblay, N.M., et al. A continuous fluorescence-based assay for the human high-molecular-weight cytosolic phospholipase A2. Anal Biochem 222 110-115 (1994).

2. Pickard, R.T., Chiou, X.G., Strifler, B.A., et al. Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginine. J Biol Chem 271 19225-19231 (1996).

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