Item № 62924
CAS № 117746-89-1
Purity ≥98%
1 mg $33.00 $0.00
5 mg $149.00 $0.00
10 mg $264.00 $0.00
25 mg $578.00 $0.00

Pricing updated 2016-04-30. Prices are subject to change without notice.

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  • 1-Palmitoyl-2-Azelaoyl PC
  • Azelaoyl PC

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.1 Many of these substances were isolated and purified from oxLDL and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position.2 PAz-PC is one of the predominant oxLDL species and may be one of the important structural determinants of oxLDL.3

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Technical Information
Formal Name 1-O-hexadecanoyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine
CAS Number 117746-89-1
  • 1-Palmitoyl-2-Azelaoyl PC
  • Azelaoyl PC
Molecular Formula C33H64NO10P
Formula Weight 665.8
Purity ≥98%
Formulation A solution in ethanol
InChI Code 1S/C33H64NO10P/c1-5-6-7-8-9-10-11-12-13-14-15-18-21-24-32(37)41-28-30(29-43-45(39,40)42-27-26-34(2,3)4)44-33(38)25-22-19-16-17-20-23-31(35)36/h30H,5-29H2,1-4H3,(H-,35,36,39,40)/t30-/m1/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Podrez, E.A., Febbraio, M., Sheibani, N., et al. Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species. J Clin Invest 105(8) 1095-1108 (2000).

2. Podrez, E.A., Batyreva, E., Shen, Z., et al. A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. J Biol Chem 277 (41) 38517-38523 (2002).

3. Itabe, H., Kudo, I., and Inoue, K. Preferential hydrolysis of oxidized phospholipids by peritoneal fluid of rats treated with casein. Biochim Biophys Acta 963 192-200 (1998 Aug 16).

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