Item № 63270
CAS № 135304-07-3
Purity ≥98%
1 mg $25.00 $0.00
5 mg $63.00 $0.00
10 mg $113.00 $0.00
25 mg $250.00 $0.00

Pricing updated 2016-05-24. Prices are subject to change without notice.

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  • AFC

N-acetyl-S-farnesyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).1,2 Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.

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Technical Information
Formal Name N-acetyl-S-(3,7,11-trimethyl-2E,6E,10-dodecatrienyl)-L-cysteine
CAS Number 135304-07-3
  • AFC
Molecular Formula C20H33NO3S
Formula Weight 367.5
Purity ≥98%
Formulation A solution in methyl acetate
InChI Code 1S/C20H33NO3S/c1-15(2)8-6-9-16(3)10-7-11-17(4)12-13-25-14-19(20(23)24)21-18(5)22/h8,10,12,19H,6-7,9,11,13-14H2,1-5H3,(H,21,22)(H,23,24)/b16-10+,17-12+

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Volker, C., Lane, P., Kwee, C., et al. A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues. FEBS Lett 295 189-194 (1991).

2. Pérez-Sala, D., Gilbert, B.A., Tan, E.W., et al. Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates. Biochem J 284 835-840 (1992).

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