Item № 89320
CAS № 88847-89-6
Purity ≥98%
1 mg $39.00 $0.00
5 mg $176.00 $0.00
10 mg $312.00 $0.00
25 mg $683.00 $0.00

Pricing updated 2016-05-01. Prices are subject to change without notice.

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  • 8-OH-dG

​8-Hydroxy-2'-deoxyguanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a measure of oxidative stress in biological systems.1,2,3,4

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Technical Information
Formal Name 2'-deoxy-8-hydroxy-guanosine
CAS Number 88847-89-6
  • 8-OH-dG
Molecular Formula C10H13N5O5
Formula Weight 283.2
Purity ≥98%
Formulation A crystalline solid
λmax 206, 249, 296 nm
SMILES NC(N1[H])=NC(N([C@H]2C[C@H](O)[C@@H](CO)O2)C(N3)=O)=C3C1=O
InChI Code 1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)/t3-,4+,5+/m0/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage Room temperature
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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QC Sheets
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References & Background Reading
Product Description References

1. Floyd, R.A. Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J 4 2587-2597 (1990).

2. Beckman, K.B., and Ames, B.N. Oxidative decay of DNA. J Biol Chem 272 19633-19636 (1997).

3. Spencer, J.P.E., Jenner, A., Chimel, K., et al. DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells. FEBS Lett 374 233-236 (1995).

4. Epe, B., Ballmaier, D., Roussyn, I., et al. DNA damage by peroxynitrite characterized with DNA repair enzymes. Nucleic Acids Res 24 4105-4110 (1996).

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