3-Thiatetradecanoic Acid
Item № 90500
CAS № 116296-31-2
Purity ≥98%
1 mg $38.00 $0.00
5 mg $171.00 $0.00
10 mg $304.00 $0.00

Pricing updated 2016-05-06. Prices are subject to change without notice.

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  • 3-TDA

3-Thiatetradecanoic acid (3-thia TDA) is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels.1 Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid via Δ9-desaturase, and dose-dependently increases Δ9-desaturase mRNA levels.2

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Technical Information
Formal Name (undecylthio)-acetic acid
CAS Number 116296-31-2
  • 3-TDA
Molecular Formula C13H26O2S
Formula Weight 246.4
Purity ≥98%
Formulation A crystalline solid
InChI Code 1S/C13H26O2S/c1-2-3-4-5-6-7-8-9-10-11-16-12-13(14)15/h2-12H2,1H3,(H,14,15)

WARNING - This product is not for human or veterinary use.

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Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Asiedu, D.K., Froyland, L., Vaagenes, H., et al. Long-term effect of tetradecylthioacetic acid: A study on plasma lipid profile and fatty acid composition and oxidation in different rat organs. Biochim Biophys Acta 1300 86-96 (1996).

2. Madsen, L., Froyland, L., Grav, H.J., et al. Up-regulated .DELTA.9-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: Accumulation of a .DELTA.9-desaturated metabolite of tetradecylthioacetic acid. J Lipid Res 38 554-563 (1997).

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