Item № 10004161
CAS № 491-70-3
Purity ≥98%
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10 mg $19.00 $0.00
50 mg $43.00 $0.00
100 mg $76.00 $0.00
500 mg $333.00 $0.00

Pricing updated 2015-11-26. Prices are subject to change without notice.

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Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets.1 Luteolin is a polyphenolic flavone found in many plants including soybeans and perilla leaves.2 Luteolin is one of the most potent flavanoid inhibitors of soybean and reticulocyte 15-lipoxygenases, with an IC50 of 0.6 µM.3 Luteolin has also been found to inhibit the release of TNFα from neutrophils, and to inhibit matrix metalloproteinases.4

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Technical Information
Formal Name 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
CAS Number 491-70-3
Molecular Formula C15H10O6
Formula Weight 286.2
Purity ≥98%
Formulation A crystalline solid
λmax 255, 348 nm
SMILES Oc1cc(O)c2c(=O)cc(oc2c1)c1ccc(O)c(O)c1
InChI Code 1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

WARNING - This product is not for human or veterinary use.

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Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
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References & Background Reading
Product Description References

1. Morton, L.W., Caccetta, R.A., Puddey, I.B., et al. Chemistry and biological effects of dietary phenolic compounds: Relevance to cardiovascular disease. Clin Exp Pharmacol Physiol 27 152-159 (2000).

2. Ueda, H., Yamazaki, C., and Yamazaki, M. Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla frutescens. Biol Pharm Bull 25(9) 1197-1202 (2002).

3. Sadik, C.D., Sies, H., and Schewe, T. Inhibition of 15-lipoxygenases by flavonoids: Structure-activity relations and mode of action. Biochem Pharmacol 65 773-781 (2003).

4. Sartor, L., Pezzato, E., Dell'Aica, I., et al. Inhibition of matrix-proteases by polyphenols: Chemical insights for anti-inflammatory and anti-invasion drug design. Biochem Pharmacol 64 229-237 (2002).

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