FABP1 (rat recombinant)
Item № 10005200
Purity ≥95%

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  • L-FABP
  • Liver-FABP
  • Fatty Acid Binding Protein 1
  • Liver-Fatty Acid Binding Protein

Fatty acid binding protein 1 (FABP1) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids.1 FABP1 is composed of ten antiparallel β strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acids. Expression of FABP1 is decreased in hepatoblastoma and hepatocellular carcinoma making the protein a potential tumor marker. Moreover, studies have suggested FABP1 as a potential biomarker for both liver and kidney injury.1 Cayman’s FABP1 has been functionally characterized by a fluorescence displacement assay using the fluorescent fatty acid analogue 11-(dansyl amino)undecanoic acid (DAUDA). Both arachidonic acid and oleic acid effectively displace DAUDA from the FABP binding pocket in a concentration-dependent manner.

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Technical Information
  • L-FABP
  • Liver-FABP
  • Fatty Acid Binding Protein 1
  • Liver-Fatty Acid Binding Protein
Purity ≥95%
Source recombinant N-terminal hexahistidine-tagged protein expressed in E. coli
MW 18.3 kDa
Formulation A solution in 50 mM of sodium phosphate, pH 7.2, containing 20% glycerol and 100 mM sodium chloride

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
Product Downloads

Download Product Insert 69 Kb PDF

Download Safety Data Sheet (SDS) 27 Kb PDF

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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QC Sheets
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References & Background Reading
Product Description References

1. Zimmerman, A.W., and Veerkamp, J.H. New insights into the structure and function of fatty acid-binding proteins. Cell Mol Life Sci 59 1096-1116 (2002).

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