DL-α-Lipoic Acid
Item № 10005728
CAS № 1077-28-7
Purity >95%
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5 g $32.00 $0.00
10 g $56.00 $0.00
25 g $123.00 $0.00

Pricing updated 2015-09-05. Prices are subject to change without notice.

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Description
Synonyms
  • Thioctic acid

DL-α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle, and acts as a general antioxidant.1,2,3 DL-α-lipoic acid can act as a direct radical scavenger, as a cofactor to regenerate reduced glutathione, and as a metal chelator.

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Technical Information
Formal Name 1,​2-​dithiolane-​3-​pentanoic acid
CAS Number 1077-28-7
Synonyms
  • Thioctic acid
Molecular Formula C8H14O2S2
Formula Weight 206.3
Purity >95%
Formulation A crystalline solid
λmax 203, 333 nm
SMILES OC(=O)​CCCCC1SSCC1
InChI Code ​1S/C8H14O2S2/c9-8(10)​4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)​
InChI Key AGBQKNBQESQNJD-UHFFFAOYSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
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Download Product Insert 85 Kb PDF

Download Safety Data Sheet (SDS) 24 Kb PDF

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Additional Information

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Inserts
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GCMS Data
References & Background Reading
Product Description References

1. Biewenga, G.P., Haenen, G.R.M.M., and Bast, A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol 29(3) 315-331 (1997).

2. Randle, P.J. Regulatory interactions between lipids and carbohydrates: The glucose fatty acid cycle after 35 years. Diabetes Metab Rev 14(4) 263-283 (1998).

3. Biewenga, G.P., Haenen, G.R.M.M., and Bast, A. The role of lipoic acid in the treatment of diabetic polyneuropathy*. Drug Metab Rev 29(4) 1025-1054 (1997).

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