Cayman Chemical Item Number 10006148

Dehydroabietylamine (CAS 1446-61-3)

See more


Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means “play”. It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.1 Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 value of 9.5 µM.2 Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.3

1. Martin, B.R. Leelamine. (2006 Apr 27).

2. Aicher, T.D., Damon, R.E., Koletar, J., et al. Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK). Bioorg Med Chem Lett 9 2223-2228 (1999).

3. Wilkerson, W., DeLucca, I., Galbraith, W., et al. Antiinflammatory phospholipase-A2 inhibitors. I. Eur J Med Chem 26 667-676 (1991).

  • Dehydroabietylamine
Formal Name 1R,​2,​3,​4,​4aS,​9,​10,​10aR-​octahydro-​1,​4a-​dimethyl-​7-​(1-​methylethyl)-​1-​phenanthrenemethanamine
CAS Number 1446-61-3
Molecular Formula C20H31N
Formula Weight 285.5
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage Room temperature
Shipping Room temperature in continental US; may vary elsewhere
Copy SMILES to clipboard
InCHI Code
Copy InCHI code to clipboard
Copy InCHI key to clipboard

Download free InCHI Key generation software

Size Price Quantity Subtotal
5 mg $29.00 $0.00
10 mg $55.00 $0.00
25 mg $131.00 $0.00
50 mg $232.00 $0.00
Bulk Contact
Cart Total $0.00

Pricing updated 2015-07-28. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

Arachidonic Acid Leelamide
Lauric Acid Leelamide
Leelamine (hydrochloride)
Show all 4 Hide all but first 3


Batch-specific Information

Get batch-specific data and documents by batch number

Separate multiple batch numbers with commas

Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA


Please wait...