AN-7

Cayman Chemical Item Number 10006212

(CAS 691410-93-2)

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Description

α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant.1 AN-7 is a more lipophilic analog of α-lipoic acid with enhanced potency and 1.5-fold increased maximal capacity to stimulate glucose transport into myocytes.2 This identifies the analogs of lipoic acid as potential new treatments for diabetes.

1. Biewenga, G.P., Haenen, G.R.M.M., and Bast, A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol 29(3) 315-331 (1997).

2. Gruzman, A., Hidmi, A., Katzhendler, J., et al. Synthesis and characterization of new and potent α-lipoic acid derivatives. Bioorg Med Chem 12 1183-1190 (2004).

Formal Name 3-​(5-​[1,​2]dithiolan-​3yl-​pentanoylamino)-​propyl]-​amide
CAS Number 691410-93-2
Molecular Formula C19H34N2O2S4
Formula Weight 450.7
Formulation A crystalline solid
Purity ≥98%
λmax 331 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O=C(CCCCC1SSCC1)​NCCCNC(=O)​CCCCC1SSCC1
InCHI Code
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​1S/C19H34N2O2S4/c22-18(8-3-1-6-16-10-14-24-26-16)​20-12-5-13-21-19(23)​9-4-2-7-17-11-15-25-27-17/h16-17H,1-15H2,(H,20,22)​(H,21,23)​
InCHI Key
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QGUXZRFEKWOQQL-UHFFFAOYSA-N

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Size Price Quantity Subtotal
1 mg $25.00 $0.00
5 mg $81.00 $0.00
10 mg $150.00 $0.00
Bulk Contact
Cart Total $0.00

Pricing updated 2015-08-04. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

Antioxidant Assay Kit
Dihydrolipoic Acid
DL-α-Lipoic Acid

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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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Ann Arbor, Michigan 48108 USA

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