AN-7 (CAS 691410-93-2) (Inchi key QGUXZRFEKWOQQL-UHFFFAOYSA-N) || Cayman Chemical | Supplier
AN-7
Item № 10006212
CAS № 691410-93-2
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $25.00 $0.00
5 mg $81.00 $0.00
10 mg $150.00 $0.00

Pricing updated 2015-08-29. Prices are subject to change without notice.

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Description

α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant.1 AN-7 is a more lipophilic analog of α-lipoic acid with enhanced potency and 1.5-fold increased maximal capacity to stimulate glucose transport into myocytes.2 This identifies the analogs of lipoic acid as potential new treatments for diabetes.

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Technical Information
Formal Name 3-​(5-​[1,​2]dithiolan-​3yl-​pentanoylamino)-​propyl]-​amide
CAS Number 691410-93-2
Molecular Formula C19H34N2O2S4
Formula Weight 450.7
Purity ≥98%
Formulation A crystalline solid
λmax 331 nm
SMILES O=C(CCCCC1SSCC1)​NCCCNC(=O)​CCCCC1SSCC1
InChI Code ​1S/C19H34N2O2S4/c22-18(8-3-1-6-16-10-14-24-26-16)​20-12-5-13-21-19(23)​9-4-2-7-17-11-15-25-27-17/h16-17H,1-15H2,(H,20,22)​(H,21,23)​
InChI Key QGUXZRFEKWOQQL-UHFFFAOYSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
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Additional Information

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References & Background Reading
Product Description References

1. Biewenga, G.P., Haenen, G.R.M.M., and Bast, A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol 29(3) 315-331 (1997).

2. Gruzman, A., Hidmi, A., Katzhendler, J., et al. Synthesis and characterization of new and potent α-lipoic acid derivatives. Bioorg Med Chem 12 1183-1190 (2004).

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