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Join us! · ENDO 2015 · San Diego, California · March 5-8, 2015 · Booth 1935
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Cayman is a manufacturer, supplier, and vendor of biochemical reagents, assay kits, forensic chemistry standards, antibodies, and proteins for scientific research. Analytical testing services and custom synthesis are also available.

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2015 Cayman Chemical Company


Cayman Chemical Item Number 10006320

Estrovis®; Ethynyl Estradiol-3-cyclopentyl ether; W 3566 (CAS 152-43-2)

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Quinestrol is a synthetic estrogen that is effective in hormone replacement therapy.1,2 It is a 3-cyclopentyl ether of ethynyl estradiol. After gastrointestinal absorption, it is stored in adipose tissue, where it is slowly released and metabolized in the liver to its active form, ethinyl estradiol. Quinestrol has found limited use in suppressing lactation in postpartum women and, in combination with synthetic progestogens, as contraceptive therapy, although additional studies are needed for both applications.

1. Baumgardner, S.B., Condrea, H., Daane, T.A., et al. Replacement estrogen therapy for menopausal vasomotor flushes. Comparison of Quinestrol and conjugated estrogens.. Obstet Gynecol 51(4) 445-452 (1978).

2. Skouby, S.O. Criteria for the selection of an optimal estrogen replacement.. Gynecol Endocrinol 15 60-67 (2001).

  • Estrovis®
  • Ethynyl Estradiol-3-cyclopentyl ether
  • W 3566
Formal Name 3-​(cyclopentyloxy)-​19-​norpregna-​1,​3,​5(10)-​trien-​20-​yn-​17α-​ol
CAS Number 152-43-2
Molecular Formula C25H32O2
Formula Weight 364.5
Formulation A crystalline solid
Purity ≥98%
λmax 202, 281 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
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Size Price Quantity Subtotal
100 mg $28.00 $0.00
250 mg $67.00 $0.00
500 mg $126.00 $0.00
1 g $224.00 $0.00
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Cart Total $0.00

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Pricing updated 2015-02-27. Prices are subject to change without notice.

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Ethynyl Estradiol


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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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