Ethynyl Estradiol

Cayman Chemical Item Number 10006486

Ethynyl 17β-Oestradiol; Ethynyl E2; Ethynyl 17β-Estradiol; Ethynyl β-Estradiol (CAS 57-63-6)

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Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.1 Ethynyl estradiol is a synthetic analog of estradiol used commonly as an oral contraceptive, often in combination with a progestin such as norgestrel/levonorgestrel or desogestrel. Efficacy of oral administration of ethynyl estradiol is facilitated by the ethynyl substitution at the C-17 position, which inhibits first pass hepatic metabolism. Ethynyl estradiol is also rapidly and almost completely absorbed from the gastrointestinal tract.2

1. Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens. N Engl J Med 346(5) 340-352 (2002).

2. Coelingh Bennink, H.J.T. Are all estrogens the same? Maturitas 47 269-275 (2003).

  • Ethynyl 17β-Oestradiol
  • Ethynyl E2
  • Ethynyl 17β-Estradiol
  • Ethynyl β-Estradiol
Formal Name 19-​norpregna-​1,​3,​5(10)-​trien-​20-​yne-​3,​17α-​diol
CAS Number 57-63-6
Molecular Formula C20H24O2
Formula Weight 296.4
Formulation A crystalline solid
Purity ≥98%
λmax 281 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
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Size Price Quantity Subtotal
500 mg $25.00 $0.00
1 g $45.00 $0.00
5 g $150.00 $0.00
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Cart Total $0.00

Pricing updated 2015-07-30. Prices are subject to change without notice.

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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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