Ethynyl Estradiol
Item № 10006486
CAS № 57-63-6
Purity ≥98%
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500 mg $25.00 $0.00
1 g $45.00 $0.00
5 g $150.00 $0.00

Pricing updated 2015-10-10. Prices are subject to change without notice.

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  • Ethynyl 17β-Oestradiol
  • Ethynyl E2
  • Ethynyl 17β-Estradiol
  • Ethynyl β-Estradiol

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.1 Ethynyl estradiol is a synthetic analog of estradiol used commonly as an oral contraceptive, often in combination with a progestin such as norgestrel/levonorgestrel or desogestrel. Efficacy of oral administration of ethynyl estradiol is facilitated by the ethynyl substitution at the C-17 position, which inhibits first pass hepatic metabolism. Ethynyl estradiol is also rapidly and almost completely absorbed from the gastrointestinal tract.2

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Technical Information
Formal Name 19-norpregna-1,3,5(10)-trien-20-yne-3,17α-diol
CAS Number 57-63-6
  • Ethynyl 17β-Oestradiol
  • Ethynyl E2
  • Ethynyl 17β-Estradiol
  • Ethynyl β-Estradiol
Molecular Formula C20H24O2
Formula Weight 296.4
Purity ≥98%
Formulation A crystalline solid
λmax 281 nm
SMILES CCC1(O)CCC2[C@@H]3CCc4cc(O)ccc4C3CC[C@]12C
InChI Code 1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
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Download Safety Data Sheet (SDS) 31 Kb PDF

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References & Background Reading
Product Description References

1. Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens. N Engl J Med 346(5) 340-352 (2002).

2. Coelingh Bennink, H.J.T. Are all estrogens the same? Maturitas 47 269-275 (2003).

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