Estradiol Benzoate
Item № 10006487
CAS № 50-50-0
Purity ≥98%
product image
500 mg $25.00 $0.00
1 g $45.00 $0.00
5 g $138.00 $0.00

Pricing updated 2015-10-10. Prices are subject to change without notice.

Bulk Inquiry Form


Enter number, size, and select unit. Example: 2 x 500 mg

Please indicate any analytical testing requirements, special handling, packaging, or delivery requirements.

  • 17β-Oestradiol Benzoate
  • β-Estradiol Benzoate
  • 17β-Estradiol 3-Benzoate
  • E2 Benzoate

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.1,2 Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. It is often used in combination with a progestin to induce estrus in domestic livestock.3 Estradiol benzoate binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM.4 This reflects a 6-10 fold reduction in binding affinity compared to estradiol.4

Download Product Insert Download Safety Data Sheet (SDS)

Related Products

Show all 10 Hide all but first 3

View Related Product Categories
Technical Information
Formal Name estra-1,3,5(10)-triene-3,17β-diol 3-benzoate
CAS Number 50-50-0
  • 17β-Oestradiol Benzoate
  • β-Estradiol Benzoate
  • 17β-Estradiol 3-Benzoate
  • E2 Benzoate
Molecular Formula C25H28O3
Formula Weight 376.5
Purity ≥98%
Formulation A crystalline solid
λmax 202, 230 nm
SMILES O=C(Oc1ccc2c(CC[C@@H]3[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]32)c1)c1ccccc1
InChI Code 1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
Product Downloads

Download Product Insert 95 Kb PDF

Download Safety Data Sheet (SDS) 27 Kb PDF

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Separate multiple batch numbers with commas

QC Sheets
Certificates of Analysis
References & Background Reading
Product Description References

1. Miller, W.L., and Tyrrell, J.B. The adrenal cortex. 3rd edition 555-711 (1995).

2. Vance, D.E. Cholesterol and related derivatives. 2nd ed. 725-748 (1988).

3. Cavalieri, J., Hepworth, G., and Macmillan, K.L. Ovarian follicular development in Holstein cows following synchronisation of oestrus with oestradiol benxoate and an intravaginal progesterone releasing insert for 5-9 days and duration of the oestrous cycle and concentrations of progesterone following ovulation. Anim Reprod Sci 81 177-193 (2004).

4. Matthews, J., Celius, T., Halgren, R., et al. Differential estrogen receptor binding of estrogenic substances: A species comparison. J Steroid Biochem Mol Biol 74 223-234 (2000).

Technical Support
Contact Us
  • To streamline the process attach the appropriate questionnaire to your inquiry.

  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Contract Research Services

We offer you the deep and diverse knowledge of more than 100 in-house scientists and the expertise that comes from more than three decades of designing and developing the tools to advance biomedical research.

Cayman is know as a partner to scientists worldwide, responding to your needs with services in:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA


Please wait...