1-Palmitoyl-2-linoleoyl PE

Cayman Chemical Item Number 10007072

(1-palmitoyl, 2-linoleoyl)-Phosphatidylethanolamine; PLPE; (1-palmitoyl, 2-linoleoyl)-Phosphoethanolamine (CAS 26662-95-3)

1-Palmitoyl-2-linoleoyl PE (CAS 26662-95-3)

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Description

Phosphatidylethanolamines are important components of cell membranes and biochemical pathways of fatty acid synthesis. 1-Palmitoyl-2-linoleoyl PE (PLPE) is one of the many phosphatidylethanolamines that may be present in cellular membranes. It has been used in studies involving the biosynthesis of anandamide via the phospholipase A2 (PLA2) and lysoPLD pathways.1 PLPE can also be used as a specific substrate to assess the activity of sPLA2-IIA in the presence of other phospholipids.2

1 Sun, Y., Tsubio, K., Okamoto, Y., et al. Biosynthesis of anandamide and N-palmitoylethanolamide by sequential actions of phospholipase A2 and lysophosphase D. J Biochem 380 749-755 (2004 Mar 3).

2 Yang, H., Mosior, M., Johnson, C.A., et al. Group-specific assays that distinguish between the four major types of mammalian phospholipase A2. Anal Biochem 269 278-288 (1999).

Synonyms
  • (1-palmitoyl, 2-linoleoyl)-Phosphatidylethanolamine
  • PLPE
  • (1-palmitoyl, 2-linoleoyl)-Phosphoethanolamine
Formal Name (1R)-​1-​[[[(2-​aminoethoxy)hydroxyphosphinyl]oxy]methyl]-​2-​[(1-​oxohexadecyl)oxy]ethyl ester,​ 9Z,​12Z-​octadecadienoic acid
CAS Number 26662-95-3
Molecular Formula C39H74NO8P
Formula Weight 716.0
Formulation A solution in chloroform
Purity ≥98%
Stability 6 months
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O=C(CCCCCCCCCCCCCCC)​OC[C@@H]​(OC(CCCCCCC/C=C\C/C=C\CCCCC)​=O)​COP([O-]​)​(OCC[NH3+]​)​=O
InCHI Code
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​1S/C39H74NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)​48-37(36-47-49(43,44)​46-34-33-40)​35-45-38(41)​31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h11,13,17-18,37H,3-10,12,14-16,19-36,40H2,1-2H3,(H,43,44)​/b13-11-,18-17-/t37-/m1/s1
InCHI Key
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HBZNVZIRJWODIB-NHCUFCNUSA-N

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1-Palmitoyl-2-linoleoyl PE is available in the following screening library:

Size Price Quantity Subtotal
5 mg $31.00 $0.00
10 mg $59.00 $0.00
50 mg $248.00 $0.00
100 mg $434.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-16. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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