Prostaglandin A2 Lipid Maps MS Standard
Cayman Chemical Item Number 10007199
PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity.1 At a 25 µM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase.2 It has also been shown to act as a vasodilator with natriuretic properties.3
1. Fukushima, M., Kato, T., Narumiya, S., et al. Prostaglandin A and J: Antitumor and antiviral prostaglandins. Adv Prostaglandin Thromboxane Leukot Res 19 415-418 (1989).
Hitomi, M., Shu, J., Strom, D., et al. Prostaglandin A2 blocks the activation of G1 phase cyclin-
Frolich, J.C., Sweetman, B.J., Carr, K., et al. Assessment of the levels of PGA2 in human plasma by gas chromatography-
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Pricing updated 2015-04-19. Prices are subject to change without notice.
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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.