20-hydroxy Prostaglandin E2 Lipid Maps MS Standard

Cayman Chemical Item Number 10007218

20-hydroxy PGE2 (CAS 57930-95-7)

20-hydroxy Prostaglandin E2 Lipid Maps MS Standard (CAS 57930-95-7)

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Description

20-hydroxy Prostaglandin E2 (20-hydroxy PGE2 is a product of cytochrome P450 metabolism of PGE2.1,2 ω-Oxidation at C-20 followed by β-oxidation and the loss of up to four carbons from the lower side chain is a prominent metabolic pathway for PGE2. 20-hydroxy PGE2 is the putative first intermediate in this chain of chemical transformations.

1 Oliw, E.H. Observations on the substrate specificity of prostaglandin hydroxylases of monkey seminal vesicles and sheep vesicular glands. Biochim Biophys Acta 1001 107-110 (1989).

2 Oliw, E.H., Fahlstadius, P., and Hamberg, M. Isolation and biosynthesis of 20-hydroxyprostaglandins E1 and E2 in ram seminal fluid. J Biol Chem 261 9216-9221 (1986).

Synonyms
  • 20-hydroxy PGE2
Formal Name 9-​oxo-​11α,​15S,​20-​trihydroxy-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 57930-95-7
Molecular Formula C20H32O6
Formula Weight 368.5
Formulation A solution in methyl acetate
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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OCCCCCC(O)​/C=C/[C@H]​1C(O)​CC(=O)​C1C/C=C\CCCC(=O)​O

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Background Reading

Oliw, E.H. Observations on the substrate specificity of prostaglandin hydroxylases of monkey seminal vesicles and sheep vesicular glands. Biochim Biophys Acta 1001 107-110 (1989).

Size Price Quantity Subtotal
50 µg $60.00 $0.00
100 µg $114.00 $0.00
500 µg $480.00 $0.00
1 mg $840.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-18. Prices are subject to change without notice.

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