20-hydroxy Prostaglandin E2 Lipid Maps MS Standard

Cayman Chemical Item Number 10007218

20-hydroxy PGE2 (CAS 57930-95-7)

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Description

20-hydroxy Prostaglandin E2 (20-hydroxy PGE2 is a product of cytochrome P450 metabolism of PGE2.1,2 ω-Oxidation at C-20 followed by β-oxidation and the loss of up to four carbons from the lower side chain is a prominent metabolic pathway for PGE2. 20-hydroxy PGE2 is the putative first intermediate in this chain of chemical transformations.

1. Oliw, E.H. Observations on the substrate specificity of prostaglandin hydroxylases of monkey seminal vesicles and sheep vesicular glands. Biochim Biophys Acta 1001 107-110 (1989).

2. Oliw, E.H., Fahlstadius, P., and Hamberg, M. Isolation and biosynthesis of 20-hydroxyprostaglandins E1 and E2 in ram seminal fluid. J Biol Chem 261 9216-9221 (1986).

Synonyms
  • 20-hydroxy PGE2
Formal Name 9-​oxo-​11α,​15S,​20-​trihydroxy-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 57930-95-7
Molecular Formula C20H32O6
Formula Weight 368.5
Formulation A solution in methyl acetate
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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OCCCCCC(O)​/C=C/[C@H]​1C(O)​CC(=O)​C1C/C=C\CCCC(=O)​O

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Background Reading

Oliw, E.H. Observations on the substrate specificity of prostaglandin hydroxylases of monkey seminal vesicles and sheep vesicular glands. Biochim Biophys Acta 1001 107-110 (1989).

Size Price Quantity Subtotal
50 µg $60.00 $0.00
100 µg $114.00 $0.00
500 µg $480.00 $0.00
1 mg $840.00 $0.00
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20-hydroxy Prostaglandin E2
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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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