2,3-dinor-11β-Prostaglandin F Lipid Maps MS Standard

Cayman Chemical Item Number 10007225

2,3-dinor-11-epi PGF; 2,3-dinor-11β-PGF (CAS 240405-20-3)

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2,3-dinor-11β-Prostaglandin F (2,3-dinor-11β-PGF) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively.1 2,3-dinor-11β-PGF has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts.2 In human asthmatic patients, 2,3-dinor-11β-PGF represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF when measured using Cayman’s 11β-PGF EIA Kit (Item No. 516521). The excretion rate for 2,3-dinor-11β-PGF is approximately 200-250 ng/24 hours in a normal adult.3

1. Liston, T.E., and Roberts, L.J. Metabolic fate of radiolabeled prostaglandin D2 in a normal human male volunteer. J Biol Chem 260 13172-13180 (1985).

2. Roberts, L.J., and Sweetman, B.J. Metabolic fate of endogenously synthesized prostaglandin D2 in a human female with mastocytosis. Prostaglandins 30 383-400 (1985).

3. O'Sullivan, S., Mueller, M.J., Dahlén, S., et al. Analyses of prostaglandin D2 metabolites in urine: Comparison between enzyme immunoassay and negative ion chemical ionization gas chromatography-mass spectrometry. Prostaglandins Other Lipid Mediat 57 149-165 (1999).

  • 2,3-dinor-11-epi PGF
  • 2,3-dinor-11β-PGF
Formal Name 9α,​11β,​15S-​trihydroxy-​2,​3-​dinor-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 240405-20-3
Molecular Formula C18H30O5
Formula Weight 326.4
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
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Size Price Quantity Subtotal
25 µg $114.00 $0.00
50 µg $217.00 $0.00
100 µg $410.00 $0.00
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Cart Total $0.00

Pricing updated 2015-07-29. Prices are subject to change without notice.

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