Thromboxane B2 Lipid Maps MS Standard
Item № 10007237
CAS № 54397-85-2
Purity ≥99%
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1 mg $55.00 $0.00
5 mg $248.00 $0.00
10 mg $440.00 $0.00

Pricing updated 2015-09-03. Prices are subject to change without notice.

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Description
Synonyms
  • TXB2

Thromboxane B2 (TXB2) is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds.1 Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis,2 while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of systemic TXA2 secretion.3,4

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Technical Information
Formal Name 9α,​11,​15S-​trihydroxythromba-​5Z,​13E-​dien-​1-​oic acid
CAS Number 54397-85-2
Synonyms
  • TXB2
Molecular Formula C20H34O6
Formula Weight 370.5
Purity ≥99%
Formulation A crystalline solid
SMILES CCCCCC(O)​/C=C/[C@H]​1OC(O)​CC(O)​C1C/C=C\CCCC(=O)​O

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
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Download Product Insert 172 Kb PDF

Download Safety Data Sheet (SDS) 24 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Needleman, P., Moncada, S., Bunting, S., et al. Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature 261 558-560 (1976).

2. Patrono, C., Ciabattoni, G., Patrignani, P., et al. Evidence for a renal origin of urinary thromboxane B2 in health and disease. Adv Prostaglandin Thromboxane Leukot Res 11 493-498 (1983).

3. Lawson, J.A., Patrono, C., Ciabattoni, G., et al. Long-lived enzymatic metabolites of thromboxane B2 in the human circulation. Anal Biochem 155 198-205 (1986).

4. Patrono, C., Ciabattoni, G., Pugliese, F., et al. Estimated rate of thromboxane secretion into the circulation of normal humans. J Clin Invest 77 590-594 (1986).

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