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Join us! · ENDO 2015 · San Diego, California · March 5-8, 2015 · Booth 1935
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Cayman is a manufacturer, supplier, and vendor of biochemical reagents, assay kits, forensic chemistry standards, antibodies, and proteins for scientific research. Analytical testing services and custom synthesis are also available.

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

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10-Thiastearic Acid

Cayman Chemical Item Number 10007417

(CAS 105099-89-6)

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Description

Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools.1,2 10-Thiastearic acid inhibits desaturation of radiolabeled stearate to oleate in rat hepatocytes and hepatoma cells by more than 80% at a concentration of 25 µM.3 This activity is associated with a hypolipidemic effect, making this 10-thiastearic acid a useful tool for evaluating new anti-obesity therapeutics.

1. Wu, P., Grav, H.J., Horn, R., et al. Effects of chain length and sulphur position of thia fatty acids on their incorporation into phospholipids in 7800 C1 hepatoma cells and isolated rat hepatocytes, and their effects on fatty acid composition of phospholipids. Biochem Pharmacol 51 751-758 (1996).

2. Pascal, R.A., and Ziering, D.L. Synthesis of heteroatom-substituted analogues of stearic acid. J Lipid Res 27 221-224 (1986).

3. Høvik, K.E., Spydevold ØS, and Bremer, J. Thia fatty acids as substrates and inhibitors of stearoyl-CoA desaturase. Biochim Biophys Acta 1349 251-256 (1997).

Formal Name 9-​(octylthio)-​nonanoic acid​
CAS Number 105099-89-6
Molecular Formula C17H34O2S
Formula Weight 302.5
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCCCCSCCCCCCCCC(O)​=O
InCHI Code
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​1S/C17H34O2S/c1-2-3-4-5-9-12-15-20-16-13-10-7-6-8-11-14-17(18)​19/h2-16H2,1H3,(H,18,19)​
InCHI Key
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OMIBNTWPNMKIGZ-UHFFFAOYSA-N

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10-Thiastearic Acid is available in the following screening library:

Size Price Quantity Subtotal
5 mg $33.00 $0.00
10 mg $63.00 $0.00
50 mg $264.00 $0.00
100 mg $462.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2015-03-03. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

3-Thiatetradecanoic Acid
Stearic Acid ethyl ester
Stearoyl Ethanolamide

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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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