L-Glutathione, reduced

Cayman Chemical Item Number 10007461

GSH (CAS 70-18-8)

L-Glutathione, reduced (CAS 70-18-8)

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Description

Glutathione (GSH) is a tripeptide (γ-glutamylcysteinylglycine) widely distributed in both plants and animals.1,2 GSH serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides.2,3 GSH is also involved in amino acid transport and maintenance of protein sulfhydryl reduction status.4,5 The concentration of GSH ranges from a few micromolar in plasma to several millimolar in tissues such as liver.

1 Foyer, C.H., Lelandais, M., and Kunert, K.J. Photooxidative stress in plants. Physiol Plant 92 696-717 (1994).

2 Bedia, C. Glutathione: Metabolism and function. (1976).

3 Baillie, T.A., and Slatter, J.G. Glutathione: A vehicle for the transport of chemically reactive metabolites in vivo. Acc Chem Res 24 264-270 (1991).

4 Inoue, M., Saito, Y., Hirata, E., et al. Regulation of redox states of plasma proteins by metabolism and transport of glutathione and related compounds. J Protein Chem 6 207-225 (1987).

5 Inoue, M. Interorgan metabolism and membrane transport of glutathione and related compounds. 225-269 (1985).

Synonyms
  • GSH
Formal Name L-​γ-​glutamyl-​L-​cysteinyl-​glycine
CAS Number 70-18-8
Molecular Formula C10H17N3O6S
Formula Weight 307.3
Formulation A crystalline solid
Purity ≥99%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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SC[C@H]​(NC(=O)​CCC(N)​C(=O)​O)​C(=O)​NCC(=O)​O
InCHI Code
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​1S/C10H17N3O6S/c11-5(10(18)​19)​1-2-7(14)​13-6(4-20)​9(17)​12-3-8(15)​16/h5-6,20H,1-4,11H2,(H,12,17)​(H,13,14)​(H,15,16)​(H,18,19)​/t5?,6-/m0/s1
InCHI Key
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RWSXRVCMGQZWBV-GDVGLLTNSA-N

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Size Price Quantity Subtotal
1 g $14.00 $0.00
5 g $63.00 $0.00
10 g $112.00 $0.00
25 g $245.00 $0.00
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Pricing updated 2014-04-17. Prices are subject to change without notice.

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