δ-CEHC

Cayman Chemical Item Number 10007706

(CAS 84599-16-6)

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Description

Molecules having vitamin E antioxidant activity include four tocopherols (α, β, γ, δ) and four tocotrienols (α, β, γ, δ).1 One form, α-tocopherol has the highest biological activity based on fetal resorption assays.2 δ-CEHC is a major β-oxidation metabolite of δ-tocopherol.3,4 Approximately 50% of a 3H-δ-tocopherol given as an intraperitoneal dose in rat is recovered in the urine as δ-CEHC, indicating this is the major route of metabolism.4

1. Kamal-Eldin, A., and Appelqvist, L. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31 671-701 (1996).

2. Weiser, H., Riss, G., and Kormann, A.F. Biodiscrimination of the eight α-tocopherol stereoisomers results in preferential accumulation of the four 2R forms in tissues and plasma of rats. J Nutr 126(10) 2539-2549 (1996).

3. Christen, S., Woodall, A.A., Shigenaga, M.K., et al. γ-Tocopherol traps mutagenic electrophiles such as NOx and complements a-tocopherol: Physiological implications. Proc Natl Acad Sci USA 94 3217-3222 (1997).

4. Chiku, S., Hamamura, K., and Nakamura, T. Novel urinary metabolite of d-δ-tocopherol in rats. J Lipid Res 25 40-48 (1984).

Formal Name 3,​4-​dihydro-​6-​hydroxy-​2,​8-​dimethyl-​2H-​1-​benzopyran-​2-​propanoic acid
CAS Number 84599-16-6
Molecular Formula C14H18O4
Formula Weight 250.3
Formulation A crystalline solid
Purity ≥95%
λmax 205, 298 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CC1=C(OC(CCC(O)​=O)​(C)​CC2)​C2=CC(O)​=C1
InCHI Code
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​1S/C14H18O4/c1-9-7-11(15)​8-10-3-5-14(2,18-13(9)​10)​6-4-12(16)​17/h7-8,15H,3-6H2,1-2H3,(H,16,17)​
InCHI Key
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BNVXCCQXUZCRSR-UHFFFAOYSA-N

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Size Price Quantity Subtotal
1 mg $29.00 $0.00
5 mg $131.00 $0.00
10 mg $232.00 $0.00
25 mg $508.00 $0.00
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