PtdIns-(1,2-dipalmitoyl) (ammonium salt) • Phosphatidylinositol C-<wbr/>16; DPPI (CAS 34290-57-8) (Inchi key MRDHBHKPDFRCJQ-VGFLHHNXSA-N) || Cayman Chemical | Supplier
PtdIns-(1,2-dipalmitoyl) (ammonium salt)
Item № 10007710
CAS № 34290-57-8
Purity ≥98%
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CART TOTAL $0.00
100 µg $50.00 $0.00
500 µg $225.00 $0.00
1 mg $400.00 $0.00

Pricing updated 2015-08-30. Prices are subject to change without notice.

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Description
Synonyms
  • Phosphatidylinositol C-16
  • DPPI

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-(1,2-dipalmitoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2), and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

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Technical Information
Formal Name 1-​(1,​2-​dihexadecanoylphosphatidyl)inositol,​ monoammonium salt
CAS Number 34290-57-8
Synonyms
  • Phosphatidylinositol C-16
  • DPPI
Molecular Formula C41H78O13P • NH4
Formula Weight 828.1
Purity ≥98%
Formulation A lyophilized powder
SMILES O[C@H]​1[C@H]​(O)​[C@@H]​(O)​[C@@H]​(O)​[C@@H]​(OP([O-]​)​(OC[C@H]​(OC(CCCCCCCCCCCCCCC)​=O)​COC(CCCCCCCCCCCCCCC)​=O)​=O)​[C@@H]​1O.[NH4+]​
InChI Code ​1S/C41H79O13P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)​51-31-33(32-52-55(49,50)​54-41-39(47)​37(45)​36(44)​38(46)​40(41)​48)​53-35(43)​30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h33,36-41,44-48H,3-32H2,1-2H3,(H,49,50)​;1H3/t33-,36-,37-,38+,39-,
InChI Key MRDHBHKPDFRCJQ-VGFLHHNXSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 88 Kb PDF

Download Safety Data Sheet (SDS) 23 Kb PDF

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Additional Information

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Inserts
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References & Background Reading
Product Description References

1. Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36 481-509 (1996).

2. Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

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