Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. A promising field of study involves controlling bacterial infections by quenching their quorum sensing systems. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-
Gould, T.A., Herman, J., Krank, J., et al. Specificity of acyl-
Morohoshi, T., Inaba, T., Kato, N., et al. Identification of quorum-
Ulrich, R.L., Hines, H.B., Parthasarathy, N., et al. Mutational analysis and biochemical characterization of the bukholderia thailandensis DW503 quorum-
Wang, L., Weng, L., Dong, Y., et al. Specificity and enzyme kinetics of the quorum-
Yates, E.A., Philipp, B., Buckley, C., et al. N-
Luo, Z., Su, S., and Farrand, S.K. In situ activation of the quorum-
Christensen, A.B., Riedel, K., Eberl, L., et al. Quorum-
Chambers, C.E., Visser, M.B., Schwab, U., et al. Identification of N-
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N-hexanoyl-L-Homoserine lactone is available in the following screening library:
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