8,11,14-Eicosatriynoic Acid • 8,11,14-<wbr/>ETI (CAS 34262-64-1) (Inchi key QLLIWTBTVOPGCM-UHFFFAOYSA-N) || Cayman Chemical | Supplier
8,11,14-Eicosatriynoic Acid
Item № 10007900
CAS № 34262-64-1
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $66.00 $0.00
5 mg $297.00 $0.00
10 mg $528.00 $0.00

Pricing updated 2015-08-29. Prices are subject to change without notice.

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Description
Synonyms
  • 8,11,14-ETI

8,11,14-Eicosatriynoic acid is an inhibitor of prostaglandin and leukotriene biosynthesis as well as arachidonic acid induced platelet aggregation.1 It inhibits cyclooxygenase (IC50 = 14 µM), human 12-lipoxygenase (IC50 = 0.46 µM), 5-lipoxygenase (IC50 = 25 µM) and the actions of slow-reacting substance of anaphylaxis (SRS-A) (IC50 = 10 µM).2,3

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Technical Information
Formal Name 8,​11,​14-​eicosatriynoic acid
CAS Number 34262-64-1
Synonyms
  • 8,11,14-ETI
Molecular Formula C20H28O2
Formula Weight 300.4
Purity ≥98%
Formulation A crystalline solid
SMILES CCCCCC#CCC#CCC#CCCCCCCC(O)​=O
InChI Code ​1S/C20H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)​22/h2-5,8,11,14-19H2,1H3,(H,21,22)​
InChI Key QLLIWTBTVOPGCM-UHFFFAOYSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
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Download Product Insert 115 Kb PDF

Download Safety Data Sheet (SDS) 23 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Goetz, J.M., Sprecher, H., Cornwell, D.G., et al. Inhibition of prostaglandin biosynthesis by triynoic acids. Prostaglandins 12(2) 187-192 (1976).

2. Sun, F.F., McGuire, J.C., Morton, D.R., et al. Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds. Prostaglandins 21(2) 333-343 (1981).

3. Jakschik, B.A., DiSantis, D.M., Sankarappa, S.K., et al. Modulation of leukotriene formation by various acetylenic acids. 127-135 (1982).

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