trans-Δ2-11-methyl-Dodecenoic Acid

Cayman Chemical Item Number 10008321

(CAS 677354-24-4)

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Description

Both prokaryotes and eukaryotes depend on small signalling molecules for cell-cell communication. trans-Δ2-11-methyl-Dodecenoic acid is the conformational isomer of cis-Δ2-11-methyl-dodecenoic acid, a diffusible signal factor (DSF) in extracellular microbial and fungal communication systems.1 In a DSF bioassay, the minimum concentration of cis-Δ2-11-methyl-dodecenoic acid required for induction of a DSF biosensor was about 0.5 µM, which is 200-fold lower than that of trans-Δ2-11-methyl-dodecenoic acid and 20,000-fold lower than that of the corresponding saturated fatty acid (11-methyl-dodecanoic acid).

1. Wang, L., He, Y., Gao, Y., et al. A bacterial cell-cell communication signal with cross-kingdom structural analogues. Mol Microbiol 51(3) 903-912 (2004).

Formal Name 11-​methyl-​2E-​dodecenoic acid
CAS Number 677354-24-4
Molecular Formula C13H24O2
Formula Weight 212.3
Formulation A crystalline solid
Purity ≥98%
λmax 208 nm
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CC(C)​CCCCCCC/C=C\C(=O)​O
InCHI Code
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​1S/C13H24O2/c1-12(2)​10-8-6-4-3-5-7-9-11-13(14)​15/h9,11-12H,3-8,10H2,1-2H3,(H,14,15)​/b11-9+
InCHI Key
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SNTXNGAQYNSTHI-PKNBQFBNSA-N

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trans-Δ2-11-methyl-Dodecenoic Acid is available in the following screening library:

Size Price Quantity Subtotal
1 mg $28.00 $0.00
5 mg $126.00 $0.00
10 mg $224.00 $0.00
50 mg $980.00 $0.00
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