PtdIns-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt)
Item № 10008398
Purity ≥98%
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100 µg $50.00 $0.00
500 µg $225.00 $0.00
1 mg $400.00 $0.00

Pricing updated 2015-11-27. Prices are subject to change without notice.

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  • Phosphatidylinositol-3,5-diphosphate C-16

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 Phosphatidylinositol (PtdIns)-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) is a synthetic analog of natural PtdIns featuring saturated C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol stereochemistry as that of the natural compound. PtdIns-(3,5)-P2 is rapidly synthesized from PtdIns-(3)-P1 in yeast when a PtdIns-(3)-P5-hydroxy kinase is activated during hyperosmotic conditions.3 PtdIns-(3,5)-P2 is also present in mammalian cells, such as monkey COS-7 cells, where a similar biosynthetic route has been demonstrated.3

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Technical Information
Formal Name 1-(1,2R-dihexadecanoylphosphatidyl)inositol-3,5-bisphosphate, trisodium salt
  • Phosphatidylinositol-3,5-diphosphate C-16
Molecular Formula C41H78O19P3 · 3Na
Formula Weight 1036.9
Purity ≥98%
Formulation A lyophilized powder
SMILES O[C@@H]1[C@H](OP([O-])(O)=O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@@H]1OP([O-])(OC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O.[Na+].[Na+].[Na+]
InChI Code 1S/C41H81O19P3.3Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)55-31-33(57-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-56-63(53,54)60-41-37(45)39(58-61(47,48)49)36(44)40(38(41)46)59-62(50,51)52;;;/h33,36-41,44-46H,3-32H2,1-2H3,(H,53,54

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
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Download Safety Data Sheet (SDS) 23 Kb PDF

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References & Background Reading
Product Description References

1. Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36 481-509 (1996).

2. Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

3. Dove, S.K., Cooke, F.T., Douglas, M.R., et al. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390 187-192 (1997).

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