D-myo-Inositol-1,5-diphosphate (sodium salt)
Item № 10008441
Purity ≥98%
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100 µg $49.00 $0.00
500 µg $221.00 $0.00
1 mg $392.00 $0.00

Pricing updated 2015-10-07. Prices are subject to change without notice.

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  • Ins(1,5)-P2 (sodium salt)
  • 1,5-IP2 (sodium salt)

D-myo-Inositol-1,5-phosphate (Ins(1,5)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals.1,2 The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate.3,4 Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.4,5

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Technical Information
Formal Name D-myo-inositol-1,5-di(hydrogen phosphate), disodium salt
  • Ins(1,5)-P2 (sodium salt)
  • 1,5-IP2 (sodium salt)
Molecular Formula C6H12O12P2 · 2Na
Formula Weight 384.1
Purity ≥98%
Formulation A lyophilized powder
SMILES O[C@@H]1[C@@H](OP([O-])(O)=O)[C@H](O)[C@@H](O)[C@@H](O)[C@H]1OP([O-])(O)=O.[Na+].[Na+]
InChI Code 1S/C6H14O12P2.2Na/c7-1-2(8)5(17-19(11,12)13)4(10)6(3(1)9)18-20(14,15)16;;/h1-10H,(H2,11,12,13)(H2,14,15,16);;/q;2*+1/p-2/t1-,2-,3-,4-,5?,6?;;/m1../s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 123 Kb PDF

Download Safety Data Sheet (SDS) 23 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Berridge, M.J. Inositol trisphosphate and calcium signalling. Nature 361 315-325 (1993).

2. Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

3. Streb, H., Irvine, R.F., Berridge, M.J., et al. Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature 306 67-69 (1983).

4. Yoshida, Y., and Imai, S. Structure and function of inositol 1,4,5-triphosphate receptor. Jpn J Pharmacol 74 125-137 (1997).

5. Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36 481-509 (1996).

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