D-myo-Inositol-1,2,3,4-tetraphosphate (sodium salt) • 1,2,3,4-<wbr/>IP<sub>4</sub> (sodium salt); Ins(1,2,3,4)-<wbr/>P<sub>4</sub> (sodium salt) (Inchi key DZJJWPAQUIBBLR-SEPOYWDNSA-J) || Cayman Chemical | Supplier
D-myo-Inositol-1,2,3,4-tetraphosphate (sodium salt)
Item № 10008448
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
100 µg $110.00 $0.00
500 µg $495.00 $0.00
1 mg $880.00 $0.00

Pricing updated 2015-08-30. Prices are subject to change without notice.

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Description
Synonyms
  • 1,2,3,4-IP4 (sodium salt)
  • Ins(1,2,3,4)-P4 (sodium salt)

D-myo-Inositol-1,2,3,4-tetraphosphate (Ins(1,2,3,4)-P4) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals.1,2,3 Ins(1,2,3,4)-P4 exhibits agonist activity at the Ins(1,4,5)-P3 receptor expressed in CHO cells where it induces Ca2+ mobilization with an ED50 value of 18.1 µM, making it nearly 180-fold less effective than Ins(1,4,5)-P3 in the same assay.4

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Technical Information
Formal Name D-​myo-​Inositol-​1,​2,​3,​4-​tetrakis(dihydrogen phosphate),​ tetrasodium salt
Synonyms
  • 1,2,3,4-IP4 (sodium salt)
  • Ins(1,2,3,4)-P4 (sodium salt)
Molecular Formula C6H12O18P4 · 4Na
Formula Weight 588.0
Purity ≥98%
Formulation A lyophilized powder
SMILES O[C@@H]​1[C@@H]​(O)​[C@H]​(OP([O-]​)​(O)​=O)​[C@@H]​(OP([O-]​)​(O)​=O)​[C@@H]​(OP([O-]​)​([OH+]​)​=O)​[C@H]​1OP([O-]​)​(O)​=O.[Na]​.[Na+]​.[Na+]​.[Na+]​
InChI Code ​1S/C6H16O18P4.4Na/c7-1-2(8)​4(22-26(12,13)​14)​6(24-28(18,19)​20)​5(23-27(15,16)​17)​3(1)​21-25(9,10)​11;;;;/h1-8H,(H2,9,10,11)​(H2,12,13,14)​(H2,15,16,17)​(H2,18,19,20)​;;;;/q;4*+1/p-4/t1-,2-,3?,4?,5?,6?;;;;/m1..../s1
InChI Key DZJJWPAQUIBBLR-SEPOYWDNSA-J

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 108 Kb PDF

Download Safety Data Sheet (SDS) 23 Kb PDF

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Additional Information

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Inserts
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GCMS Data
References & Background Reading
Product Description References

1. Berridge, M.J. Inositol trisphosphate and calcium signalling. Nature 361 315-325 (1993).

2. Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

3. Shears, S.B. The versatility of inositol phosphates as cellular signals. Biochim Biophys Acta 1436 49-67 (1998).

4. Burford, N.T., Nahorski, S.R., Chung, S., et al. Binding and activity of the nine possible regioisomers of myo-inositol tetrakisphosphate at the inositol 1,4,5-trisphosphate receptor. Cell Calcium 21 301-310 (1997).

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