γ-Tocotrienol (CAS 14101-61-2) (Inchi key OTXNTMVVOOBZCV-WAZJVIJMSA-N) || Cayman Chemical | Supplier
γ-Tocotrienol
Item № 10008494
CAS № 14101-61-2
Purity ≥98%
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CART TOTAL $0.00
1 mg $21.00 $0.00
5 mg $95.00 $0.00
10 mg $168.00 $0.00
25 mg $368.00 $0.00

Pricing updated 2015-08-31. Prices are subject to change without notice.

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Description

The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1 Tocotrienols are found in high concentrations in palm oil and rice bran. Recent studies observe that tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2 Spontaneously hypertensive rats fed a diet which includes γ-tocotrienol show significant reduction of systolic blood pressure and an increase of nitric oxide synthase activity in blood vessels.3 γ-Tocotrienol at 20 µM induces apoptosis of malignant sympathoadrenal (+SA) murine mammary epithelial cells.4

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Technical Information
Formal Name 3,​4-​dihydro-​2,​7,​8-​trimethyl-​2R-​[(3E,​7E)-​4,​8,​12-​trimethyl-​3,​7,​11-​tridecatrienyl]-​2H-​1-​benzopyran-​6-​ol
CAS Number 14101-61-2
Molecular Formula C28H42O2
Formula Weight 410.6
Purity ≥98%
Formulation A solution in ethanol
λmax 297 nm
SMILES C[C@]​1(CC/C=C(C)​/CC/C=C(C)​/CC/C=C(C)​/C)​OC2=C(C)​C(C)​=C(O)​C=C2CC1
InChI Code ​1S/C28H42O2/c1-20(2)​11-8-12-21(3)​13-9-14-22(4)​15-10-17-28(7)​18-16-25-19-26(29)​23(5)​24(6)​27(25)​30-28/h11,13,15,19,29H,8-10,12,14,16-18H2,1-7H3/b21-13+,22-15+/t28-/m1/s1
InChI Key OTXNTMVVOOBZCV-WAZJVIJMSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
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Additional Information

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References & Background Reading
Product Description References

1. Kamal-Eldin, A., and Appelqvist, L. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31 671-701 (1996).

2. Osakada, F., Hashino, A., Kume, T., et al. α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology 47 904-915 (2004).

3. Shah, S., and Sylvester, P.W. Tocotrienol-induced caspase-8 activation is unrelated to death receptor apoptotic signaling in neoplastic mammary epithelial cells. Exp Biol Med 229 745-755 (2004).

4. Newaz, M.A., Yousefipour, Z., Nawal, N., et al. Nitric oxide synthase activity in blood vessels of spontaneously hypertensive rats: Antioxidant protection by γ-tocotrienol. J Physiol Pharmacol 54(3) 319-327 (2003).

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