δ-Tocotrienol

Cayman Chemical Item Number 10008513

(CAS 25612-59-3)

See more

Description

The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1 Tocotrienols are found in high concentrations in palm oil and rice bran. Recent studies observe that tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2 At 0.1-10 µM, δ-tocotrienol significantly suppresses H2O2-induced cell death of rat striatal neurons and provides protection against S-nitrocysteine-induced cell death and SIN-1 cytotoxicity in a concentration dependant manner.2 At concentrations of 10 µM, δ-tocotrienol displays more inhibitory action on adhesiveness of HAECs to U937 monocytic cells, via inhibition of VCAM-1 expression, than α-tocopherol and other tocotrienols at the same concentration.3

1. Kamal-Eldin, A., and Appelqvist, L. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31 671-701 (1996).

2. Osakada, F., Hashino, A., Kume, T., et al. α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology 47 904-915 (2004).

3. Naito, Y., Shimozawa, M., Kuroda, M., et al. Tocotrienols reduce 25-hydroxycholesterol-induced monocyte-endothelial cell interaction by inhibiting the surface expresion of adhesion molecules. Atherosclerosis 180 19-25 (2005).

Formal Name 3,​4-​dihydro-​2,​8-​dimethyl-​2R-​[(3E,​7E)-​4,​8,​12-​trimethyl-​3,​7,​11-​tridecatrienyl]-​2H-​1-​benzopyran-​6-​ol
CAS Number 25612-59-3
Molecular Formula C27H40O2
Formula Weight 396.6
Formulation A solution in ethanol
Purity ≥98%
λmax 298 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
C/C(CC/C=C(C)​/CC/C=C(C)​/C)​=C\CC[C@@]​1(C)​OC2=C(C)​C=C(O)​C=C2CC1
InCHI Code
Copy InCHI code to clipboard
​1S/C27H40O2/c1-20(2)​10-7-11-21(3)​12-8-13-22(4)​14-9-16-27(6)​17-15-24-19-25(28)​18-23(5)​26(24)​29-27/h10,12,14,18-19,28H,7-9,11,13,15-17H2,1-6H3/b21-12+,22-14+/t27-/m1/s1
InCHI Key
Copy InCHI key to clipboard
ODADKLYLWWCHNB-LDYBVBFYSA-N

Download free InCHI Key generation software

δ-Tocotrienol is available in the following screening library:

Size Price Quantity Subtotal
1 mg $21.00 $0.00
5 mg $95.00 $0.00
10 mg $168.00 $0.00
25 mg $368.00 $0.00
Bulk Contact
Cart Total $0.00

Pricing updated 2015-08-03. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

α-CEHC
(±)-α-CMBHC
α-Tocotrienol
β-Tocotrienol
γ-CEHC
γ-Tocotrienol
Show all 6 Hide all but first 3

Downloads

Batch-specific Information

Get batch-specific data and documents by batch number


Separate multiple batch numbers with commas

Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

JOIN OUR SOCIAL NETWORK!

Please wait...