δ-Tocotrienol
Item № 10008513
CAS № 25612-59-3
Purity ≥98%
product image
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $21.00 $0.00
5 mg $95.00 $0.00
10 mg $168.00 $0.00
25 mg $368.00 $0.00

Pricing updated 2015-09-02. Prices are subject to change without notice.

Bulk Inquiry Form

X

Enter number, size, and select unit. Example: 2 x 500 mg

Please indicate any analytical testing requirements, special handling, packaging, or delivery requirements.

Description

The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1 Tocotrienols are found in high concentrations in palm oil and rice bran. Recent studies observe that tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2 At 0.1-10 µM, δ-tocotrienol significantly suppresses H2O2-induced cell death of rat striatal neurons and provides protection against S-nitrocysteine-induced cell death and SIN-1 cytotoxicity in a concentration dependant manner.2 At concentrations of 10 µM, δ-tocotrienol displays more inhibitory action on adhesiveness of HAECs to U937 monocytic cells, via inhibition of VCAM-1 expression, than α-tocopherol and other tocotrienols at the same concentration.3

Download Product Insert Download Safety Data Sheet (SDS)

Related Products

Show all 6 Hide all but first 3

View Related Product Categories
View Screening Libraries with δ-Tocotrienol
Technical Information
Formal Name 3,​4-​dihydro-​2,​8-​dimethyl-​2R-​[(3E,​7E)-​4,​8,​12-​trimethyl-​3,​7,​11-​tridecatrienyl]-​2H-​1-​benzopyran-​6-​ol
CAS Number 25612-59-3
Molecular Formula C27H40O2
Formula Weight 396.6
Purity ≥98%
Formulation A solution in ethanol
λmax 298 nm
SMILES C/C(CC/C=C(C)​/CC/C=C(C)​/C)​=C\CC[C@@]​1(C)​OC2=C(C)​C=C(O)​C=C2CC1
InChI Code ​1S/C27H40O2/c1-20(2)​10-7-11-21(3)​12-8-13-22(4)​14-9-16-27(6)​17-15-24-19-25(28)​18-23(5)​26(24)​29-27/h10,12,14,18-19,28H,7-9,11,13,15-17H2,1-6H3/b21-12+,22-14+/t27-/m1/s1
InChI Key ODADKLYLWWCHNB-LDYBVBFYSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
Product Downloads

Download Product Insert 107 Kb PDF

Download Safety Data Sheet (SDS) 35 Kb PDF

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Separate multiple batch numbers with commas

Inserts
QC Sheets
Certificates of Analysis
GCMS Data
References & Background Reading
Product Description References

1. Kamal-Eldin, A., and Appelqvist, L. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31 671-701 (1996).

2. Osakada, F., Hashino, A., Kume, T., et al. α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology 47 904-915 (2004).

3. Naito, Y., Shimozawa, M., Kuroda, M., et al. Tocotrienols reduce 25-hydroxycholesterol-induced monocyte-endothelial cell interaction by inhibiting the surface expresion of adhesion molecules. Atherosclerosis 180 19-25 (2005).

Technical Support
Contact Us
  • To streamline the process attach the appropriate questionnaire to your inquiry.

  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Contract Research Services

We offer you the deep and diverse knowledge of more than 100 in-house scientists and the expertise that comes from more than three decades of designing and developing the tools to advance biomedical research.

Cayman is know as a partner to scientists worldwide, responding to your needs with services in:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

JOIN OUR SOCIAL NETWORK!

Please wait...