5-cis-15(R)-Iloprost
Item № 10008588
Purity ≥97%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
500 µg $107.00 $0.00
1 mg $203.00 $0.00
5 mg $856.00 $0.00
10 mg $1,498.00 $0.00

Pricing updated 2015-09-03. Prices are subject to change without notice.

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Description
Synonyms
  • 5-cis-15(R)-Ciloprost

5-cis-15(R)-Iloprost is the C-5 cis-isomer and 15(R)-epimer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.1 There are no published studies of the pharmacological properties of 5-cis-15(R)-iloprost.

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Technical Information
Formal Name 6,​9α-​methylene-​11α,​15R-​dihydroxy-​16-​methyl-​prosta-​5Z,​13E-​dien-​18-​yn-​1-​oic acid
Synonyms
  • 5-cis-15(R)-Ciloprost
Molecular Formula C22H32O4
Formula Weight 360.5
Purity ≥97%
Formulation A solution in methyl acetate
SMILES O[C@@H]​1C[C@H]​2[C@H]​(C/C(C2)​=C\CCCC(O)​=O)​[C@H]​1/C=C/[C@H]​(O)​C(C)​CC#CC
InChI Code ​1S/C22H32O4/c1-3-4-7-15(2)​20(23)​11-10-18-19-13-16(8-5-6-9-22(25)​26)​12-17(19)​14-21(18)​24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)​/b11-10+,16-8-/t15?,17-,18+,19-,20-,21+/m0/s1
InChI Key HIFJCPQKFCZDDL-KESZHIOGSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
Product Downloads

Download Product Insert 109 Kb PDF

Download Safety Data Sheet (SDS) 33 Kb PDF

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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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Inserts
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GCMS Data
References & Background Reading
Product Description References

1. Schrör, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) - equipotent to PGI2 in vitro. Naunyn Schmiedebergs Arch Pharmacol 316 252-255 (1981).

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