15-keto Iloprost

Cayman Chemical Item Number 10008616

15-keto Iloprost

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Description

15-keto Iloprost is the C-15 oxidized derivative of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.1 There are no published studies of the pharmacological properties of 15-keto iloprost.

1 Schrör, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) - equipotent to PGI2 in vitro. Naunyn Schmiedebergs Arch Pharmacol 316 252-255 (1981).

Formal Name 6,​9α-​methylene-​11α-​hydroxy-​15-​keto-​16-​methyl-​prosta-​5E,​13E-​dien-​18-​yn-​1-​oic acid
Molecular Formula C22H30O4
Formula Weight 358.5
Formulation A solution in methyl acetate
Purity ≥97%
λmax 236 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O[C@@H]​1C[C@H]​2[C@H]​(C/C(C2)​=C/CCCC(O)​=O)​[C@H]​1/C=C/C(C(C)​CC#CC)​=O
InCHI Code
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​1S/C22H30O4/c1-3-4-7-15(2)​20(23)​11-10-18-19-13-16(8-5-6-9-22(25)​26)​12-17(19)​14-21(18)​24/h8,10-11,15,17-19,21,24H,5-7,9,12-14H2,1-2H3,(H,25,26)​/b11-10+,16-8+/t15?,17-,18+,19-,21+/m0/s1
InCHI Key
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LDICATDQJSBQOX-JNSFOOLWSA-N

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Size Price Quantity Subtotal
500 µg $107.00 $0.00
1 mg $203.00 $0.00
5 mg $856.00 $0.00
10 mg $1,498.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-21. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Iloprost

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Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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