Pinolenic Acid Exclusive

Cayman Chemical Item Number 10008654

(CAS 16833-54-8)

Pinolenic Acid (CAS 16833-54-8)

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Description

Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils. Both oils have been found to have lipid-lowering properties. A diet containing maritime pine seed oil (MPSO) lowered HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux in vitro.1 Korean pine seed oil supplements may help in obesity by reduction of appetite. People taking this oil had an increase in the satiety hormones CCK and GLP-1 and a reduced desire to eat.2 The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not converted to arachidonic acid metabolically and can reduce arachidonic acid levels in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%.3

1 Asset, G., Leroy, A., Bauge, E., et al. Effects of dietary maritime pine (Pinus pinaster)-seed oil on high-density lipoprotein levels and in vitro cholesterol efflux in mice expressing human apolipoprotein A-I. Br J Nutr 84 353-360 (2000).

2 Causey, J.L. Korean pine nut fatty acids induce satiety-producing hormone release in overweight human volunteers. The 231st ACS National Meeting (2006 28 March).

3 Tamotsu, T., Tatsunori, T., Morishige, J., et al. Non-methylene-interrupted polyunsaturated fatty acids: Effective substitute for arachidonate of phosphatidylinositol. Biochem Biophys Res Commun 264 683-688 (1999).

Formal Name 5Z,​9Z,​12Z-​octadecatrienoic acid
CAS Number 16833-54-8
Molecular Formula C18H30O2
Formula Weight 278.4
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C/C=C\CC/C=C\CCCC(=O)​O
InCHI Code
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​1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)​20/h6-7,9-10,13-14H,2-5,8,11-12,15-17H2,1H3,(H,19,20)​/b7-6-,10-9-,14-13-
InCHI Key
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HXQHFNIKBKZGRP-URPRIDOGSA-N

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Pinolenic Acid is available in the following screening libraries:

Size Price Quantity Subtotal
10 mg $19.00 $0.00
25 mg $45.00 $0.00
50 mg $86.00 $0.00
100 mg $152.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-16. Prices are subject to change without notice.

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Related Products

9(Z),11(E),13(E)-Octadecatrienoic Acid methyl ester
Docosahexaenoic Acid
Eicosapentaenoic Acid
Pinolenic Acid ethyl ester
Pinolenic Acid methyl ester
Stearidonic Acid
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