Item № 10009145
CAS № 41859-67-0
Purity ≥98%
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500 mg $9.00 $0.00
1 g $17.00 $0.00
5 g $72.00 $0.00
10 g $126.00 $0.00

Pricing updated 2015-11-30. Prices are subject to change without notice.

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  • Benzofibrate
  • BM 15075
  • Bezalip
  • Bezatrol
  • Difaterol

Bezafibrate is a well established pan-peroxisome proliferator-activated receptor (pan-PPAR) activator. This fibrate drug has over 25 years of therapeutic use with a good safety profile. The fibrate class of drugs are generally known as PPARα agonists, but bezafibrate appears to activate PPARδ and PPARγ as well. Bezafibrate activates human PPARα, PPARδ, and PPARγ with EC50 values of 50, 20, and 60 µM, respectively, in a cell-based transcription assay.1 Bezafibrate is used to treat hyperlipidemia. It helps lower low-density lipoprotein cholesterol and triglycerides while raising high-density lipoprotein cholesterol levels. It also improves insulin sensitivity and reduces blood glucose levels, which in combination with the cholesterol effects significantly lowers the incidence of cardiovascular events and development of diabetes in patients with features of metabolic syndrome.2

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Technical Information
Formal Name 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic acid
CAS Number 41859-67-0
  • Benzofibrate
  • BM 15075
  • Bezalip
  • Bezatrol
  • Difaterol
Molecular Formula C19H20ClNO4
Formula Weight 361.8
Purity ≥98%
Formulation A crystalline solid
λmax 229 nm
InChI Code 1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
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Download Product Insert 122 Kb PDF

Download Safety Data Sheet (SDS) 26 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Willson, T.M., Brown, P.J., Sternbach, D.D., et al. The PPARs: From orphan receptors to drug discovery. J Med Chem 43(4) 528-550 (2000).

2. Tenenbaum, A., Motro, M., and Fisman, E.Z. Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: The bezafibrate lessons. Cardiovasc Diabetol 4(14) 1-5 (2005).

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