Cayman Chemical Item Number 10009634
Small molecules that promote osteoblast differentiation might be useful as therapeutic agents for bone diseases such as osteoporosis. Purmorphamine is a 2,6,9-
Wu, X., Ding, Q., Gray, N.S., et al. A small molecule with osteogenesis-
2. Beloti, M.M., Bellesini, L.S., and Rosa, A.L. Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells. Cell Biol Int 29(7) 537-541 (2005).
3. Wu, X., Walker, J., Zhang, J., et al. Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Chem Biol 11 1229-1238 (2004).
4. Sinha, S., and Chen, J.K. Purmorphamine activates the hedgehog pathway by targeting smoothened. Nat Chem Biol 2(1) 29-30 (2006).
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Purmorphamine is available in the following screening libraries:
Pricing updated 2015-03-31. Prices are subject to change without notice.
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